A Reproductive Lexicon


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gene knockout/knockin

A technique that manipulates one of an organism's genes to understand its function, either by deletion (gene knockout: abbreviation KO) or insertion (gene knockin: abbreviation KI). Gene knockout/knockin is induced by a Cre-LoxP system that deletes or inserts genes of interest. Double knockout (abbreviation DKO) is the deletion of two genes simultaneously. 

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