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Cre-LoxP recombination

A site-specific recombinase technology that is targeted to a specific time and cell type of gene deletions and insertions. The Cre-Lox system is performed by Cre recombinase that recombines the LoxP sites derived from bacteriophage P1. It has been a very useful tool to understand the role of tissue-specific genes and mutant genes that are lethal, if expressed globally.