A Reproductive Lexicon


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anti-mullerian hormone

Anti-mullerian hormone (AMH) is a hormone secreted by the Sertoli cells in the embryonic developing testes of males. AMH represses the development of the Mullerian Duct (also called paramesonephric ducts, developing female reproductive tract). AMH is also secreted by granulos cells of preantral and smaller antral follicels in the adult ovary. During male embryonic development, AMH insures the regression of female structures (fallopina tubes, uterus, cervix, and upper vagina), enabling the proper development of the wolffian duct (male reproductive tract, vas deferens, seminal vesicles). In the female, AMH secretion occurs during the reproductive lifespan until menopause; because of this, AMH can be used as a marker of the ovarian reserve.