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Aneuploidy traces back to the point of cell division when chromosomes are not separated properly and refers to a state in which a cell or cells has/have too many or too few chromosomes. This is often seen in the form of trisomy, such as Trisomy 21 (Down syndrome), or monosomy, such as Turners Syndrome. In female gametes, aneuploidy can lead to miscarriages, infertility, and birth defects.